Christian B. Anfinsen
American biochemist (1916–1995)
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United StatesHe proved that a protein's shape — the fold that makes it work — is written into its sequence. The 1972 Nobel recognized the insight that function follows from chemistry alone.
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Christian Boehmer Anfinsen Jr. was born March 26, 1916. His work centered on ribonuclease, a protein he used to demonstrate that amino acid sequence determines three-dimensional structure without outside instruction. That principle — later known as Anfinsen's dogma — became foundational to molecular biology. He shared the 1972 Nobel Prize in Chemistry with Stanford Moore and William Howard Stein for the discovery. Anfinsen died May 14, 1995.
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