Swiss chemist (born 1938)
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He made it possible to see the three-dimensional shape of proteins in solution — without crystals, without destroying them — by turning NMR spectroscopy into a tool for mapping the architecture of life at the molecular level.
Kurt Wüthrich was born on 4 October 1938 in Aarberg, a small town in Canton of Bern, Switzerland. Trained as a chemist and biophysicist, he spent his career solving a problem that had stymied structural biology: how to determine the precise shape of biological macromolecules without forcing them into artificial crystal forms. He developed nuclear magnetic resonance methods that could reveal protein structures in solution, closer to their natural state. The work earned him the Nobel Prize in Chemistry. His techniques opened a new route into understanding how proteins fold, move, and function —…
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