John Fenn
American analytical chemist (1917–2010)
United StatesSummary
Updated 2026-05-29
Pioneered electrospray ionization, a now-standard technique in mass spectrometry that earned him a 2002 Nobel Prize in Chemistry. Fenn spent decades moving between jet propulsion research and molecular beams before landing on the analytical chemistry work that stuck.
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John Bennett Fenn was an American professor of analytical chemistry who was awarded a share of the Nobel Prize in Chemistry in 2002. He shared half of the award with Koichi Tanaka for their work in mass spectrometry. The other half went to Kurt Wüthrich. Fenn's contributions specifically related to the development of electrospray ionization, now a commonly used technique for large molecules and routine liquid chromatography-tandem mass spectrometry. Early in his career, he studied the field of jet propulsion at Project SQUID and focused on molecular beams. He finished his career with more than…
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