American pharmacologist (1915–1974)
He cracked the code on how hormones actually talk to cells — the invisible courier system that turns a shot of adrenaline into a racing heart, a surge of energy, a body reorganized in seconds.
Born in Burlingame, Kansas on November 19, 1915, Sutherland built his career in pharmacology and biochemistry chasing a single elegant question: how does a hormone standing outside a cell make anything happen inside it? The answer arrived in cyclic adenosine monophosphate — cyclic AMP — a tiny molecule that ferries the signal across the membrane, the "second messenger" that translates one chemical language into another. His work on epinephrine and the mechanics of hormone action earned him the Nobel Prize in Physiology or Medicine in 1971. He died on March 9, 1974, three years after Stockholm,…
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