4th-century BC Macedonian princess and queen regent of Epirus
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Alexander the Great's sister, Cleopatra ruled Epirus as queen regent after their father Philip II's death. Her bloodline made her one of antiquity's most politically connected women—though history mostly forgot her.
Cleopatra of Macedonia, or Cleopatra of Epirus was an ancient Macedonian princess and later queen regent of Epirus. The daughter of Philip II of Macedon and Olympias of Epirus, she was the only full sibling of Alexander the Great. Her other siblings include half sisters Thessalonike and Cynane, and half-brother Philip III of Macedon.
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