Medical patient
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S.M., sometimes referred to as SM-046, is an American woman with a peculiar type of brain damage that physiologically reduces her ability to feel fear. First described by scientists in 1994, she has had exclusive and complete bilateral amygdala destruction since late childhood as a consequence of Urbach–Wiethe disease. Dubbed by the media as the "woman with no fear", S.M. has been studied extensively in scientific research; she has helped researchers elucidate the function of the amygdala.
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