Roberts Bartholow

Roberts Bartholow or Roobert Bartholow was an American physician and a professor at several American medical colleges. He is best known for his experiments involving a 30-year-old patient named Mary Rafferty. Rafferty was admitted to Good Samaritan Hospital in Cincinnati, Ohio in 1874 with a 2-inch-diameter (51 mm) hole in her skull caused by a cancerous ulcer. Bartholow experimented with applying current to Rafferty's exposed dura using needle electrodes. His report detailed the first observations of how electrical stimulation of the brain affects motor functions of the body, but many ethical concerns were raised about the way in which he carried out his experiments. Rafferty went into a coma for three days and then died the day after coming out of the coma from a massive seizure.