Byzantine noble
Manuel Palaiologos was the youngest son of Thomas Palaiologos, a brother of Constantine XI Palaiologos, the final Byzantine emperor. Thomas took Manuel and the rest of his family to Corfu after the Fall of Constantinople in 1453 and the subsequent Ottoman invasion of the Morea in 1460. After Thomas's death in 1465, the children moved to Rome, where they were initially taken care of by Cardinal Bessarion and were provided with money and housing by the papacy.
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