American fur trader (1772–1820)
Manuel Lisa, also known as Manuel de Lisa, was a Spanish citizen and later American citizen who, while living on the western frontier, became a landowner, merchant, fur trader, United States Indian agent, and explorer. Lisa was among the founders, in St. Louis, of the Missouri Fur Company, an early fur trading company. Manuel Lisa gained respect through his trading among Native American tribes of the upper Missouri River region, such as the Teton Sioux, Omaha and Ponca.
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