Irwin Fridovich
✓ Source-basedfallingAmerican biochemist (1929-2019)
Irwin Fridovich was an American biochemist who, together with his graduate student Joe M. McCord, discovered the enzymatic activity of copper-zinc superoxide dismutase (SOD), - to protect organisms from the toxic effects of superoxide free radicals formed as a byproduct of normal oxygen metabolism.
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Edgar Fahs SmithAlso won Elliott Cresson Medal
Nathan SharonAlso won honorary doctor of Paris Descartes University
James Mapes DodgeAlso won Elliott Cresson Medal
James WyngaardenAlso won North Carolina Award for ScienceJules FrançoisAlso won honorary doctor of Paris Descartes UniversityAbout this person
Irwin Fridovich was an American biochemist who, together with his graduate student Joe M. McCord, discovered the enzymatic activity of copper-zinc superoxide dismutase (SOD), - to protect organisms from the toxic effects of superoxide free radicals formed as a byproduct of normal oxygen metabolism. Subsequently, Fridovich's research group also discovered the manganese-containing and the iron-containing SODs from Escherichia coli and the mitochondrial MnSOD (SOD2), now known to be an essential protein in mammals. He spent the rest of his career studying the biochemical mechanisms of SOD and of biological superoxide toxicity, using bacteria as model systems. Fridovich was also Professor Emeritus of Biochemistry at Duke University.
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