Lady Irene Drusilla Namaganda was the first woman to have the title of Nnabagerekka of the kingdom of Buganda. She was Nnabagerekka and first wife of Kabaka (king) Daudi Chwa II and Nnamasole to her son Mutesa II. She was deposed as Nnamasole in a notorious public trial for having a relationship with a commoner.