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Holden Karnofsky

American nonprofit executive · Born 1981 · age 45

Holden G. Karnofsky is an American nonprofit executive. Karnofsky co-founded the charity evaluator GiveWell with Elie Hassenfeld in 2007. He co-founded in 2014 the grantmaking organization Open Philanthropy, and was its CEO and later co-CEO until 2023. He joined Anthropic in 2025.

Holden Karnofsky is read about 834 times a day, in 6 languages.

A typical day, 30 days to 10 November 2026

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2018“I think it's somewhat of a happy coincidence so far that most breakthroughs have been good. To say, I see a breakthrough on the horizon. Is that good or bad?”In their wordsFebruary 2018In an interview with Robert Wiblin, February 2018; also quoted by Ben Pace in "Extended Quote on the Institution of Academia" and by Rob

2014“I model the world as having most of the impact from extreme cases, 'home-runs'. I think that's true in business, science and social impact.”In their wordsJanuary 2014In an interview with Benjamin Todd, January 2014

“I could tell you about my strengths and weaknesses.”In their wordsJanuary 2014In an interview with Benjamin Todd, January 2014

2007“The issue, it seems to me, is that many people think of giving the same way they think of eating broccoli: they feel obligated to, they know they should, but they'd rather not.”In their wordsJanuary 2007In "Chocolate-covered broccoli", January 2007

1981Born

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  1. My sense is that factory farms do a great deal of damage to the world that isn't included in the prices of their products.

    On the "Ethics" page of his Power Smoothie website, Own words

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Born 1981 · age 45