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Helen Hobbs
American molecular geneticist · United States · On the map · Academics · Born 1952 · age 74
Helen Haskell Hobbs is an American medical researcher who is professor at the University of Texas Southwestern Medical Center, and a Howard Hughes Medical Institute Investigator, who won a 2016 Breakthrough Prize in Life Sciences and the 2018 Harrington Prize for Innovation in Medicine.
Helen Hobbs is read about 9 times a day, in 10 languages.
A typical day, 30 days to 28 July 2026
The middle day of the days counted, so one week of news cannot move it. The line under it is the last 60 days, one point a day.
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About this person
Hobbs specializes in the dysregulation of lipid metabolism and how it affects human diseases. She and Jonathan C. Cohen found that people with hypomorphic PCSK9 mutations had lower LDL-cholesterol levels and were almost immune to heart disease. This finding led to the development of a new class of cholesterol-lowering drugs that mimic the effects of the PCSK9 mutations. She and Cohen also identified the first genetic risk factor for fatty liver disease, a burgeoning health problem that can lead to cirrhosis and liver cancer. Their laboratory has shown that mutation in PNPLA3 causes accumulation of PNPLA3 on lipid droplets, which compromises the mobilization of triglycerides from liver cells. She sits on the Board of Directors at Pfizer.
