# Tak Wah Mak

> Tak Wah Mak, is a Canadian medical researcher, geneticist, oncologist, and biochemist. He first became widely known for his discovery of the T-cell receptor in 1983 and pioneering work in the genetics of immunology. In 1995, Mak published a landmark paper on the discovery of the function of the immune checkpoint protein CTLA-4, thus opening the path for immunotherapy/checkpoint inhibitors as a means of cancer treatment. Mak is also the founder of Agios Pharmaceuticals, whose lead compound, IDHIFA®, was approved by the FDA for acute myeloid leukemia in August 2017, becoming the first drug specifically targeting cancer metabolism to be used for cancer treatment. He has worked in a variety of areas including biochemistry, immunology, and cancer genetics.

*Canadian biochemist*

**Canonical URL:** https://fame.am/person/tak-wah-mak

## Identity
- **Profile type:** Academic ([Wikidata](https://www.wikidata.org/entity/Q39631))
- **Category:** Academics
- **Country:** Canada
- **Born:** 1946-10-04
- **Status:** living
- **Gender:** male

## Bio

Imported from discovery source: wikidata-dump

## Fame
- **Popularity score:** 45.0 / 100
- **Momentum:** 0.3 / 100  (trend: FALLING)
- **Historical depth:** 7.9 / 100
- **Now attention:** 0.0 / 100
- **Source confidence:** 50.0 / 100
- **Profile completeness:** 55.0 / 100

## Sources
- [麦德华](https://zh.wikipedia.org/wiki/%E9%BA%A6%E5%BE%B7%E5%8D%8E)
- [تاك واه ماك](https://ar.wikipedia.org/wiki/%D8%AA%D8%A7%D9%83_%D9%88%D8%A7%D9%87_%D9%85%D8%A7%D9%83)
- [Tak Wah Mak](https://de.wikipedia.org/wiki/Tak_Wah_Mak)
- [Tak Wah Mak](https://en.wikipedia.org/wiki/Tak_Wah_Mak)
- [Tak Wah Mak](https://eu.wikipedia.org/wiki/Tak_Wah_Mak)
- [麦徳華](https://ja.wikipedia.org/wiki/%E9%BA%A6%E5%BE%B3%E8%8F%AF)
- [Tak Wah Mak](https://pt.wikipedia.org/wiki/Tak_Wah_Mak)
- [Tak Wah Mak](https://sl.wikipedia.org/wiki/Tak_Wah_Mak)
- [麥德華](https://zh_yue.wikipedia.org/wiki/%E9%BA%A5%E5%BE%B7%E8%8F%AF)
- [Wikidata](https://www.wikidata.org/wiki/Q2389051)

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