# Fame.am profile — machine-readable export
# Canonical URL: https://fame.am/person/jesse-gelsinger
# Generated: 2026-08-13T01:35:48.853Z

schema: https://schema.org/Person
url: "https://fame.am/person/jesse-gelsinger"
name: "Jesse Gelsinger"
slug: "jesse-gelsinger"
description: "Jesse Gelsinger was the first person publicly identified as having died in a clinical trial for gene therapy. Gelsinger suffered from ornithine transcarbamylase deficiency, an X-linked genetic disease of the liver, the symptoms of which include an inability to metabolize ammonia – a byproduct of protein breakdown. The disease is usually fatal at birth, but Gelsinger had a milder form of the disease, in which the ornithine transcarbamylase gene is mutated in only part of the patient's cells, a condition known as somatic mosaicism. As his deficiency was partial, Gelsinger managed to survive on a restricted diet and special medications."
tagline: "American man who died during a clinical trial (1981–1999)"
image: "https://upload.wikimedia.org/wikipedia/en/thumb/a/aa/JesseGelsingerROIsmall.tif/lossy-page1-250px-JesseGelsingerROIsmall.tif.jpg"
gender: "male"
country:
  name: "United States"
  isoCode: "US"
birthDate: "1981-06-18"
deathDate: "1999-09-17"
livingStatus: "DECEASED"
scores:
  popularity:           46.16
  momentum:             0
  historical:           5.549430666666667
  currentAttention:     0
  sourceConfidence:     35
  profileCompleteness:  50
  trendDirection:       "FALLING"
ranks:
  global:   null
  country:  null
  category: null
sources:
  - url: "https://fi.wikipedia.org/wiki/Jesse_Gelsinger"
    title: "Jesse Gelsinger"
    type:  "WIKIPEDIA"
  - url: "https://en.wikipedia.org/wiki/Jesse_Gelsinger"
    title: "Jesse Gelsinger"
    type:  "WIKIPEDIA"
  - url: "https://es.wikipedia.org/wiki/Jesse_Gelsinger"
    title: "Jesse Gelsinger"
    type:  "WIKIPEDIA"
  - url: "https://sl.wikipedia.org/wiki/Jesse_Gelsinger"
    title: "Jesse Gelsinger"
    type:  "WIKIPEDIA"
  - url: "https://fr.wikipedia.org/wiki/Jesse_Gelsinger"
    title: "Jesse Gelsinger"
    type:  "WIKIPEDIA"
  - url: "https://ru.wikipedia.org/wiki/%D0%93%D0%B5%D0%BB%D1%81%D0%B8%D0%BD%D0%B3%D0%B5%D1%80%2C_%D0%94%D0%B6%D0%B5%D1%81%D1%81%D0%B8"
    title: "Гелсингер, Джесси"
    type:  "WIKIPEDIA"
  - url: "https://www.wikidata.org/wiki/Q2825818"
    title: "Wikidata"
    type:  "WIKIDATA"

# bio (long form, separated for readability)
bio: |
  Imported from discovery source: wikidata-dump