# Jerome Karle

> He cracked the atomic geometry of crystals without needing to build models first — a mathematical leap that let scientists see the architecture of matter directly from X-ray scatter, work that earned him a Nobel in 1985.

*American physical chemist (1918–2013)*

**Canonical URL:** https://fame.am/person/jerome-karle

## Identity
- **Profile type:** Scientist ([Wikidata](https://www.wikidata.org/entity/Q39631))
- **Category:** Scientists
- **Country:** United States
- **Born:** 1918-06-18
- **Died:** 2013-06-06
- **Status:** deceased
- **Gender:** male

## Bio

Jerome Karle was born Jerome Karfunkle on June 18, 1918. A physical chemist by training, he spent years developing methods to solve one of chemistry's hardest puzzles: determining the three-dimensional arrangement of atoms in a crystal from diffraction patterns alone. Working alongside Herbert A. Hauptman, Karle devised direct mathematical techniques that bypassed the trial-and-error guesswork that had dominated the field. The Nobel Prize in Chemistry came in 1985, recognizing a breakthrough that opened the door to rapid structure determination across biology, materials science, and drug design. He died on June 6, 2013, a week shy of his ninety-fifth birthday.

## Fame
- **Popularity score:** 53.0 / 100
- **Momentum:** 1.7 / 100  (trend: STABLE)
- **Historical depth:** 22.0 / 100
- **Now attention:** 9.2 / 100
- **Source confidence:** 60.0 / 100
- **Profile completeness:** 70.0 / 100

## Topics
#Scientists, #Scientist, #Chemistry, #United States, #Americas, #20th Century

## Sources
- [Wikipedia](https://en.wikipedia.org/wiki/Jerome_Karle)
- [Wikidata](https://www.wikidata.org/wiki/Q106733)
- [Pantheon 2.0](https://pantheon.world/profile/person/Jerome%20Karle)
- [جروم کارل](https://azb.wikipedia.org/wiki/%D8%AC%D8%B1%D9%88%D9%85_%DA%A9%D8%A7%D8%B1%D9%84)
- [Cerom Karle](https://az.wikipedia.org/wiki/Cerom_Karle)
- [Джэром Карле](https://be.wikipedia.org/wiki/%D0%94%D0%B6%D1%8D%D1%80%D0%BE%D0%BC_%D0%9A%D0%B0%D1%80%D0%BB%D0%B5)
- [Джером Карл](https://bg.wikipedia.org/wiki/%D0%94%D0%B6%D0%B5%D1%80%D0%BE%D0%BC_%D0%9A%D0%B0%D1%80%D0%BB)
- [জেরোম কার্ল](https://bn.wikipedia.org/wiki/%E0%A6%9C%E0%A7%87%E0%A6%B0%E0%A7%8B%E0%A6%AE_%E0%A6%95%E0%A6%BE%E0%A6%B0%E0%A7%8D%E0%A6%B2)
- [Jerome Karle](https://ca.wikipedia.org/wiki/Jerome_Karle)
- [Jerome Karle](https://cs.wikipedia.org/wiki/Jerome_Karle)
- [Jerome Karle](https://da.wikipedia.org/wiki/Jerome_Karle)
- [Jerome Karle](https://de.wikipedia.org/wiki/Jerome_Karle)
- [Jerome Karle](https://es.wikipedia.org/wiki/Jerome_Karle)
- [Jerome Karle](https://et.wikipedia.org/wiki/Jerome_Karle)
- [Jerome Karle](https://eu.wikipedia.org/wiki/Jerome_Karle)
- [جروم کارل](https://fa.wikipedia.org/wiki/%D8%AC%D8%B1%D9%88%D9%85_%DA%A9%D8%A7%D8%B1%D9%84)
- [Jerome Karle](https://fi.wikipedia.org/wiki/Jerome_Karle)
- [Jerome Karle](https://fr.wikipedia.org/wiki/Jerome_Karle)
- [Jerome Karle](https://gd.wikipedia.org/wiki/Jerome_Karle)
- [Jerome Karle](https://gl.wikipedia.org/wiki/Jerome_Karle)
- [Jerome Karle](https://hak.wikipedia.org/wiki/Jerome_Karle)
- [ג'רום קרל](https://he.wikipedia.org/wiki/%D7%92'%D7%A8%D7%95%D7%9D_%D7%A7%D7%A8%D7%9C)
- [Jerome Karle](https://hu.wikipedia.org/wiki/Jerome_Karle)
- [Ջերոմ Կառլե](https://hy.wikipedia.org/wiki/%D5%8B%D5%A5%D6%80%D5%B8%D5%B4_%D4%BF%D5%A1%D5%BC%D5%AC%D5%A5)
- [Jerome Karle](https://id.wikipedia.org/wiki/Jerome_Karle)
- [جيروم كارل](https://ar.wikipedia.org/wiki/%D8%AC%D9%8A%D8%B1%D9%88%D9%85_%D9%83%D8%A7%D8%B1%D9%84)
- [جيروم كارل](https://arz.wikipedia.org/wiki/%D8%AC%D9%8A%D8%B1%D9%88%D9%85_%D9%83%D8%A7%D8%B1%D9%84)

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