# Irwin Rose

> He figured out how cells take out the trash — and won a Nobel for it. Rose spent decades unraveling ubiquitin, the molecular tag that marks proteins for destruction, a system so fundamental that without it nothing in your body would work right.

*American biologist (1926-2015)*

**Canonical URL:** https://fame.am/person/irwin-rose

## Identity
- **Profile type:** Scientist ([Wikidata](https://www.wikidata.org/entity/Q39631))
- **Category:** Scientists
- **Country:** United States
- **Born:** 1926-07-16
- **Died:** 2015-06-02
- **Status:** deceased
- **Gender:** male

## Bio

Irwin Allan Rose was born July 16, 1926, an American biologist who would spend his career in the molecular shadows where proteins live and die. The breakthrough came with Aaron Ciechanover and Avram Hershko: together they discovered ubiquitin-mediated protein degradation, the elegant cellular mechanism that tags worn-out or misfolded proteins for disposal. The work earned all three the 2004 Nobel Prize in Chemistry, recognition that one of biology's most essential quality-control systems had finally been mapped. Rose died June 2, 2015, having shown that destruction, properly ordered, is as vital as creation.

## Fame
- **Popularity score:** 54.9 / 100
- **Momentum:** 5.8 / 100  (trend: RISING)
- **Historical depth:** 22.0 / 100
- **Now attention:** 32.1 / 100
- **Source confidence:** 60.0 / 100
- **Profile completeness:** 70.0 / 100

## Topics
#Scientists, #Academic, #Chemistry, #Biology, #United States, #Americas, #20th Century

## Sources
- [Wikipedia](https://en.wikipedia.org/wiki/Irwin_Rose)
- [Wikidata](https://www.wikidata.org/wiki/Q230652)
- [Pantheon 2.0](https://pantheon.world/profile/person/Irwin%20Rose)
- [اروین روز](https://azb.wikipedia.org/wiki/%D8%A7%D8%B1%D9%88%DB%8C%D9%86_%D8%B1%D9%88%D8%B2)
- [İrvin Rouz](https://az.wikipedia.org/wiki/%C4%B0rvin_Rouz)
- [Ірвін Роўз](https://be.wikipedia.org/wiki/%D0%86%D1%80%D0%B2%D1%96%D0%BD_%D0%A0%D0%BE%D1%9E%D0%B7)
- [Ъруин Роуз](https://bg.wikipedia.org/wiki/%D0%AA%D1%80%D1%83%D0%B8%D0%BD_%D0%A0%D0%BE%D1%83%D0%B7)
- [আরউইন রোজ](https://bn.wikipedia.org/wiki/%E0%A6%86%E0%A6%B0%E0%A6%89%E0%A6%87%E0%A6%A8_%E0%A6%B0%E0%A7%8B%E0%A6%9C)
- [Irwin Rose](https://ca.wikipedia.org/wiki/Irwin_Rose)
- [Irwin Rose](https://cs.wikipedia.org/wiki/Irwin_Rose)
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- [اروین روز](https://fa.wikipedia.org/wiki/%D8%A7%D8%B1%D9%88%DB%8C%D9%86_%D8%B1%D9%88%D8%B2)
- [Irwin Rose](https://fi.wikipedia.org/wiki/Irwin_Rose)
- [Irwin Rose](https://fr.wikipedia.org/wiki/Irwin_Rose)
- [Irwin Rose](https://ga.wikipedia.org/wiki/Irwin_Rose)
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- [אירווין רוז](https://he.wikipedia.org/wiki/%D7%90%D7%99%D7%A8%D7%95%D7%95%D7%99%D7%9F_%D7%A8%D7%95%D7%96)
- [इरविन रोज](https://hi.wikipedia.org/wiki/%E0%A4%87%E0%A4%B0%E0%A4%B5%E0%A4%BF%E0%A4%A8_%E0%A4%B0%E0%A5%8B%E0%A4%9C)
- [Իրվին Ռոզ](https://hy.wikipedia.org/wiki/%D4%BB%D6%80%D5%BE%D5%AB%D5%B6_%D5%8C%D5%B8%D5%A6)
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