# Fame.am profile — machine-readable export
# Canonical URL: https://fame.am/person/helen-hobbs
# Generated: 2026-08-14T06:16:27.230Z

schema: https://schema.org/Person
url: "https://fame.am/person/helen-hobbs"
name: "Helen Hobbs"
slug: "helen-hobbs"
description: "Helen Haskell Hobbs is an American medical researcher who is professor at the University of Texas Southwestern Medical Center, and a Howard Hughes Medical Institute Investigator, who won a 2016 Breakthrough Prize in Life Sciences and the 2018 Harrington Prize for Innovation in Medicine. Hobbs specializes in the dysregulation of lipid metabolism and how it affects human diseases. She and Jonathan C. Cohen found that people with hypomorphic PCSK9 mutations had lower LDL-cholesterol levels and were almost immune to heart disease. This finding led to the development of a new class of cholesterol-lowering drugs that mimic the effects of the PCSK9 mutations. She and Cohen also identified the first genetic risk factor for fatty liver disease, a burgeoning health problem that can lead to cirrhosis and liver cancer. Their laboratory has shown that mutation in PNPLA3 causes accumulation of PNPLA3 on lipid droplets, which compromises the mobilization of triglycerides from liver cells. She sits on the Board of Directors at Pfizer."
tagline: "American molecular geneticist"
gender: "female"
country:
  name: "United States"
  isoCode: "US"
category:
  name: "Academics"
  slug: "academics"
profileType:
  name: "Academic"
  slug: "academic"
  entityType: "https://www.wikidata.org/entity/Q39631"
birthDate: "1952-05-05"
livingStatus: "LIVING"
scores:
  popularity:           43.03
  momentum:             2.088353413654619
  historical:           9.144169333333334
  currentAttention:     0
  sourceConfidence:     54.99999999999999
  profileCompleteness:  55
  trendDirection:       "FALLING"
ranks:
  global:   null
  country:  null
  category: null
sources:
  - url: "https://ru.wikipedia.org/wiki/%D0%A5%D0%BE%D0%B1%D0%B1%D1%81%2C_%D0%A5%D0%B5%D0%BB%D0%B5%D0%BD"
    title: "Хоббс, Хелен"
    type:  "WIKIPEDIA"
  - url: "https://ar.wikipedia.org/wiki/%D9%87%D9%8A%D9%84%D9%8A%D9%86_%D9%87%D9%88%D8%A8%D8%B2"
    title: "هيلين هوبز"
    type:  "WIKIPEDIA"
  - url: "https://arz.wikipedia.org/wiki/%D9%87%D9%8A%D9%84%D9%8A%D9%86_%D9%87%D9%88%D8%A8%D8%B2"
    title: "هيلين هوبز"
    type:  "WIKIPEDIA"
  - url: "https://de.wikipedia.org/wiki/Helen_Hobbs"
    title: "Helen Hobbs"
    type:  "WIKIPEDIA"
  - url: "https://en.wikipedia.org/wiki/Helen_Hobbs"
    title: "Helen Hobbs"
    type:  "WIKIPEDIA"
  - url: "https://fr.wikipedia.org/wiki/Helen_Hobbs"
    title: "Helen Hobbs"
    type:  "WIKIPEDIA"
  - url: "https://he.wikipedia.org/wiki/%D7%94%D7%9C%D7%9F_%D7%94%D7%95%D7%91%D7%A1"
    title: "הלן הובס"
    type:  "WIKIPEDIA"
  - url: "https://ja.wikipedia.org/wiki/%E3%83%98%E3%83%AC%E3%83%B3%E3%83%BB%E3%83%9B%E3%83%83%E3%83%96%E3%82%B9"
    title: "ヘレン・ホッブス"
    type:  "WIKIPEDIA"
  - url: "https://pl.wikipedia.org/wiki/Helen_Hobbs"
    title: "Helen Hobbs"
    type:  "WIKIPEDIA"
  - url: "https://pt.wikipedia.org/wiki/Helen_Hobbs"
    title: "Helen Hobbs"
    type:  "WIKIPEDIA"
  - url: "https://www.wikidata.org/wiki/Q21433424"
    title: "Wikidata"
    type:  "WIKIDATA"

# bio (long form, separated for readability)
bio: |
  Imported from discovery source: wikidata-dump